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Exome sequencing reveals variants in known and novel candidate genes for severe sperm motility disorders

7 Apr 2021

Abstract excerpt

STUDY QUESTION: What are the causative genetic variants in patients with male infertility due to severe sperm motility disorders? SUMMARY ANSWER: We identified high confidence disease-causing variants in multiple genes previously associated with severe sperm motility disorders in 10 out of 21 patients (48%) and variants in novel candidate genes in seven additional patients (33%). WHAT IS KNOWN ALREADY: Severe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34089056
DOI: 10.1093/humrep/deab099

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