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Utility of exome sequencing in primary spermatogenic disorders: From research to diagnostics

19 Sept 2024

Abstract excerpt

BACKGROUND: Primary spermatogenic disorders represent a severe form of male infertility whereby sperm production is impaired due to testicular dysfunction, leading to reduced quality or quantity of spermatozoa. Gene-centered research has certainly demonstrated the importance of the genetic factor in the etiology of both poor sperm morphology or motility and reduced sperm count. In the last decade, next-generation...

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PMID: 39300832
DOI: 10.1111/andr.13753

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