Article
The Association between Polluted Neighborhoods and TP53-Mutated Non-Small Cell Lung Cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2021
Erhunmwunsee Loretta, Wing Sam E, Shen Jenny, Hu Hengrui, Sosa Ernesto, Lopez Lisa N, Raquel Catherine, Sur Melissa, Ibarra-Noriega Pilar, Currey Madeline, Lee Janet, Kim Jae Y, Raz Dan J, Amini Arya, Sampath Sagus, Koczywas Marianna, Massarelli Erminia, West Howard L, Reckamp Karen L, Kittles Rick A, Salgia Ravi, Seewaldt Victoria L, Neuhausen Susan L, Gray Stacy W
Abstract excerpt
BACKGROUND: Poor patients often reside in neighborhoods of lower socioeconomic status (SES) with high levels of airborne pollutants. They also have higher mortality from non-small cell lung cancer (NSCLC) than those living in wealthier communities. We investigated whether living in polluted neighborhoods is associated with somatic mutations linked with lower survival rates, i.e., TP53 mutations. METHODS: In a...
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