Article
Neighborhood disadvantage is associated with KRAS-mutated non-small cell lung cancer risk.
Journal of cancer research and clinical oncology - 1 Jul 2023
Wing Sam E, Jankowska Marta M, Zou Xiaoke, Sosa Ernesto, Yang Jiue-An, Benmarhnia Tarik, Neuhausen Susan L, Nelson Rebecca, Salgia Ravi, Gray Stacy W, Erhunmwunsee Loretta
Abstract excerpt
PURPOSE: It remains unclear why individuals living in disadvantaged neighborhoods have shorter non-small cell lung cancer (NSCLC) survival. It is possible that living in these deprived areas is linked with increased risk of developing aggressive NSCLC biology. Here, we explored the association of somatic KRAS mutations, which are associated with shorter survival in NSCLC patients, and 11 definitions of...
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