Article
Generation of three human iPSC lines from PLAN (PLA2G6-associated neurodegeneration) patients.
Stem cell research - 1 May 2021
Machuca Candela, Correa-Vela Marta, García-Navas Deyanira, Darling Alejandra, Villalón-García Irene, Sánchez-Alcázar José Antonio, Pérez-Dueñas Belén, Erceg Slaven, Espinós Carmen
Abstract excerpt
The human iPSC cell lines, PLANFiPS1-Sv4F-1 (RCPFi004-A), PLANFiPS2-Sv4F-1 (RCPFi005-A), PLANFiPS3-Sv4F-1 RCPFi006-A), derived from dermal fibroblast from three patients suffering PLAN (PLA2G6-associated neurodegeneration; MIM 256600) caused by mutations in the PLA2G6 gene, was generated by non-integrative reprogramming technology using OCT3/4, SOX2, CMYC and KLF4 reprogramming factors. The pluripotency was...
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