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Generation of two human iPSC lines, HMGUi004-A and FINCBi004-A, from fibroblasts of MPAN patients carrying pathogenic recessive mutations in the gene C19orf12.

Stem cell research - 1 Oct 2023

Zanuttigh Enrica, Rusha Ejona, Peron Camille, Brunetti Dario, Zorzi Giovanna, Pertek Anna, Nteli Polyxeni, Winkelmann Juliane, Tiranti Valeria, Iuso Arcangela

Abstract excerpt

Mitochondrial membrane Protein-Associated Neurodegeneration (MPAN) is a lethal neurodegenerative disorder caused by mutations in the human gene C19orf12. The molecular mechanisms underlying the disorder are still unclear, and no established therapy is available. Here, we describe the generation and characterization of two human induced pluripotent stem cell (iPSC) lines derived from skin fibroblasts of two MPAN...

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PMID: 37689041
DOI: 10.1016/j.scr.2023.103197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Generation of two human iPSC lines, HMGUi004-A and FINCBi004-A, from fibroblasts of MPAN patients carrying pathogenic recessive mutations in the gene C19orf12.PMID 37689041Read ↗

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