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Article

TIGA: target illumination GWAS analytics.

Bioinformatics (Oxford, England) - 5 Nov 2021

Yang Jeremy J, Grissa Dhouha, Lambert Christophe G, Bologa Cristian G, Mathias Stephen L, Waller Anna, Wild David J, Jensen Lars Juhl, Oprea Tudor I

Abstract excerpt

MOTIVATION: Genome-wide association studies can reveal important genotype-phenotype associations; however, data quality and interpretability issues must be addressed. For drug discovery scientists seeking to prioritize targets based on the available evidence, these issues go beyond the single study. RESULTS: Here, we describe rational ranking, filtering and interpretation of inferred gene-trait associations and...

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Identifiers

PMID: 34086846
DOI: 10.1093/bioinformatics/btab427
PMCID: PMC11025677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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