Article
Multifactorial Landscape Parses to Reveal a Predictive Model for Knee Osteoarthritis.
International journal of environmental research and public health - 31 May 2021
Singh Monica, Valecha Srishti, Khinda Rubanpal, Kumar Nitin, Singh Surinderpal, Juneja Pawan K, Kaur Taranpal, Di Napoli Mario, Minhas Jatinder S, Singh Puneetpal, Mastana Sarabjit
Abstract excerpt
The present study attempted to investigate whether concerted contributions of significant risk variables, pro-inflammatory markers, and candidate genes translate into a predictive marker for knee osteoarthritis (KOA). The present study comprised 279 confirmed osteoarthritis patients (Kellgren and Lawrence scale >2) and 287 controls. Twenty SNPs within five genes (CRP, COL1A1, IL-6, VDR, and eNOS), four...
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