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Using Existing Drugs as Leads for Broad Spectrum Anthelmintics Targeting Protein Kinases

14 Feb 2013

Abstract excerpt

As one of the largest protein families, protein kinases (PKs) regulate nearly all processes within the cell and are considered important drug targets. Much research has been conducted on inhibitors for PKs, leading to a wealth of compounds that target PKs that have potential to be lead anthelmintic drugs. Identifying compounds that have already been developed to treat neglected tropical diseases is an attractive...

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PMID: 23459584
DOI: 10.1371/journal.ppat.1003149

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