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Genetics and Epigenetics of One-Carbon Metabolism Pathway in Autism Spectrum Disorder: A Sex-Specific Brain Epigenome?

Genes - 20 May 2021

Tisato Veronica, Silva Juliana A, Longo Giovanna, Gallo Ines, Singh Ajay V, Milani Daniela, Gemmati Donato

Abstract excerpt

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition affecting behavior and communication, presenting with extremely different clinical phenotypes and features. ASD etiology is composite and multifaceted with several causes and risk factors responsible for different individual disease pathophysiological processes and clinical phenotypes. From a genetic and epigenetic side, several candidate...

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PMID: 34065323
DOI: 10.3390/genes12050782
PMCID: PMC8161134

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