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Article

Preliminary evidence for involvement of the folate gene polymorphism 19bp deletion-DHFR in occurrence of autism.

Neuroscience letters - 5 Jul 2007

Adams Michelle, Lucock Mark, Stuart John, Fardell Sean, Baker Kerrie, Ng Xiaowei

Abstract excerpt

Folate has long been implicated in both the metabolism of neurotransmitter molecules, and as an agonist with a direct effect upon neuronal tissue. Folates mediate transfer of one-carbon units into major biosynthetic pathways. From a developmental perspective, the most important reactions are de novo methionine and thymine synthesis, critical for DNA expression and elaboration, respectively. Dihydrofolate...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17597297
DOI: 10.1016/j.neulet.2007.05.025

Genes

DHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Preliminary evidence for involvement of the folate gene polymorphism 19bp deletion-DHFR in occurrence of autism.PMID 17597297Read ↗

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