Article
Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL).
Cells - 11 May 2021
Sitlinger Andrea, Deal Michael A, Garcia Erwin, Thompson Dana K, Stewart Tiffany, MacDonald Grace A, Devos Nicolas, Corcoran David, Staats Janet S, Enzor Jennifer, Weinhold Kent J, Brander Danielle M, Weinberg J Brice, Bartlett David B
Abstract excerpt
Chronic lymphocytic leukemia (CLL) is associated with physical dysfunction and low overall fitness that predicts poor survival following the commencement of treatment. However, it remains unknown whether higher fitness provides antioncogenic effects. We identified ten fit (CLL-FIT) and ten less fit (CLL-UNFIT) treatment-naïve CLL patients from 144 patients who completed a set of physical fitness and performance...
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