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Article

Factors Associated with Mutations: Their Matching Rates to Cardiovascular and Neurological Diseases.

International journal of molecular sciences - 11 May 2021

Lucas Hannah B, McKnight Ian, Raines Regan, Hijazi Abdullah, Hart Christoph, Lee Chan, Kim Do-Gyoon, Li Wei, Lee Peter H U, Shim Joon W

Abstract excerpt

Monogenic hypertension is rare and caused by genetic mutations, but whether factors associated with mutations are disease-specific remains uncertain. Given two factors associated with high mutation rates, we tested how many previously known genes match with (i) proximity to telomeres or (ii) high adenine and thymine content in cardiovascular diseases (CVDs) related to vascular stiffening. We extracted genomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34064609
DOI: 10.3390/ijms22105057
PMCID: PMC8151074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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