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Article

Genes causing congenital hydrocephalus: Their chromosomal characteristics of telomere proximity and DNA compositions.

Experimental neurology - 1 Jan 2021

McKnight Ian, Hart Christoph, Park In-Hyun, Shim Joon W

Abstract excerpt

Congenital hydrocephalus (CH) is caused by genetic mutations, but whether factors impacting human genetic mutations are disease-specific remains elusive. Given two factors associated with high mutation rates, we reviewed how many disease-susceptible genes match with (i) proximity to telomeres or (ii) high adenine and thymine (A + T) content in human CH as compared to other disorders of the central nervous system...

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Identifiers

PMID: 33157092
DOI: 10.1016/j.expneurol.2020.113523
PMCID: PMC7750280

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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