Article
Constitutive and latent immune mechanisms exert 'silent' control of virus infections in the central nervous system.
Current opinion in immunology - 1 Oct 2021
Paludan Soren R, Mogensen Trine H
Abstract excerpt
Viral infections in the central nervous system (CNS) can lead to severe disease manifestations often mediated by a combination of viral cytopathic effects and immunopathology. Moreover, neuronal tissue and brain activities are highly sensitive to excessive inflammation that disturb homeostasis. Immune responses to virus infections in the CNS should therefore be tightly balanced and limited in magnitude and...
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