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Article

Modeling Human Fetal Hematopoiesis in Humanized Mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Keita Seydou, Canque Bruno, Alhaj Hussen Kutaiba

Abstract excerpt

Due to difficulties to access primary human bone marrow samples and age or donor effects, human hematopoiesis has long remained far less well characterized than in the mouse. Despite recent progresses in single-cell RNA profiling only little is known as to phenotype, function and developmental trajectories of human lymphomyeloid progenitors and precursors. This is especially true regarding the developmental...

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PMID: 34057726
DOI: 10.1007/978-1-0716-1425-9_17

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