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High-throughput PBTK models for in vitro to in vivo extrapolation

31 May 2021

Abstract excerpt

Introduction Toxicity data are unavailable for many thousands of chemicals in commerce and the environment. Therefore, risk assessors need to rapidly screen these chemicals for potential risk to public health. High-throughput screening (HTS) for in vitro bioactivity, when used with high-throughput toxicokinetic (HTTK) data and models, allows characterization of these thousands of chemicals.Areas covered This...

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PMID: 34056988
DOI: 10.1080/17425255.2021.1935867

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