Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid Molecular Detection of Terbinafine-resistant Dermatophytes

1 Jan 2021

Abstract excerpt

Terbinafine (TRF)-resistant Trichophyton interdigitale and Trichophyton rubrum have been isolated from human patients. These strains have missense mutations (Leu393Ser/Phe or Phe397Leu) in the squalene epoxidase-encoding gene, SQLE. We developed a PCR detection method to identify hotspot mutation sites in SQLE genes of dermatophytes. To sequence hotspots in isolates, we prepared primers based on conserved...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fungal Infections and Studies
Share to Nail Diseases and Treatments
Share to Plant Pathogens and Fungal Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34053979
DOI: 10.3314/mmj.21-00001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid Molecular Detection of Terbinafine-resistant DermatophytesPMID 34053979Read ↗

Evaluation of DermaGenius ® resistance real‐time polymerase chain reaction for rapid detection of terbinafine‐resistant Trichophyton speciesSemantic proximity Read ↗

Increased terbinafine resistance among clinical genotypes of Trichophyton mentagrophytes/T. interdigitale species complex harboring squalene epoxidase gene mutations.Semantic proximity Read ↗

Evaluation of the DermaGenius® Resistance Multiplex Real-Time PCR assay for rapid identification and detection of terbinafine resistant Trichophyton mentagrophytes and Trichophyton rubrum species complex.Semantic proximity Read ↗

Rapid detection of terbinafine resistance in Trichophyton species by Amplified refractory mutation system-polymerase chain reactionSemantic proximity Read ↗

Terbinafine Resistance in Dermatophytes: A French Multicenter Prospective StudySemantic proximity Read ↗

Terbinafine resistance is associated with newly developed point mutations in squalene epoxidase gene in Trichophyton rubrum and T. mentagrophytes/T. indotineae species complexSemantic proximity Read ↗

Genomic epidemiology of emerging terbinafine-resistant Trichophyton indotineaeSemantic proximity Read ↗

Phylogeny, Antifungal Susceptibility, and Point Mutations of SQLE Gene in Major Pathogenic Dermatophytes Isolated From Clinical DermatophytosisSemantic proximity Read ↗

First Reported Cases of Terbinafine‐Resistant Trichophyton indotineae Isolates in Israel: Epidemiology, Clinical Characteristics and Response to TreatmentSemantic proximity Read ↗

Mutation in the Squalene Epoxidase Gene of Trichophyton interdigitale and Trichophyton rubrum Associated with Allylamine ResistanceSemantic proximity Read ↗

Antifungal Susceptibility and Mutations in the Squalene Epoxidase Gene in Dermatophytes of the Trichophyton mentagrophytes Species Complex.Semantic proximity Read ↗

High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.