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Article

Whole Exome Sequencing for the Identification of Mutations in CD8+ T-Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Cox Sharon Natasha

Abstract excerpt

Advances in next-generation sequencing and in particular whole exome sequencing (WES) have provided an innovative opportunity to perform a mutational screening of the entire coding region of the genome down to the single base, enhancing the discovery of causal mutations important for disease treatment and management. Recently, the accumulation of germline mutations in expanded CD8+ T-cells has been found to have...

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Identifiers

PMID: 34053057
DOI: 10.1007/978-1-0716-1507-2_11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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