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Article

Middle Ear and Temporal Bone Nonkeratinizing Squamous Cell Carcinomas With DEK-AFF2 Fusion: An Emerging Entity.

The American journal of surgical pathology - 1 Sept 2020

Todorovic Emilija, Truong Tra, Eskander Antoine, Lin Vincent, Swanson David, Dickson Brendan C, Weinreb Ilan

Abstract excerpt

Primary squamous cell carcinomas (SCCs) of the middle ear and temporal bone are rare and usually keratinizing by morphology. Nonkeratinizing, basaloid SCCs arising in this area are exceedingly rare, and, due to the anatomic proximity to the skull base, nasopharynx, and nasal sinuses, the differential diagnosis is broad. Most tumors with squamous differentiation arising in these subsites are either viral-induced...

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PMID: 32366754
DOI: 10.1097/PAS.0000000000001498

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