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Article

Enumeration of major peripheral blood leukocyte populations for multicenter clinical trials using a whole blood phenotyping assay.

Journal of visualized experiments : JoVE - 16 Sept 2012

Hensley Tiffany R, Easter Austin B, Gerdts Sarah E, De Rosa Stephen C, Heit Antje, McElrath M Juliana, Andersen-Nissen Erica

Abstract excerpt

Cryopreservation of peripheral blood leukocytes is widely used to preserve cells for immune response evaluations in clinical trials and offers many advantages for ease and standardization of immunological assessments, but detrimental effects of this process have been observed on some cell subsets, such as granulocytes, B cells, and dendritic cells. Assaying fresh leukocytes gives a more accurate picture of the in...

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Identifiers

PMID: 23007739
DOI: 10.3791/4302
PMCID: PMC3490252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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