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Article

Identification of COL3A1 variants associated with sporadic thoracic aortic dissection: a case-control study.

Frontiers of medicine - 1 Jun 2021

Chen Yanghui, Sun Yang, Li Zongzhe, Li Chenze, Xiao Lei, Dai Jiaqi, Li Shiyang, Liu Hao, Hu Dong, Wu Dongyang, Hu Senlin, Yu Bo, Chen Peng, Xu Ping, Kong Wei, Wang Dao Wen

Abstract excerpt

Thoracic aortic dissection (TAD) without familial clustering or syndromic features is known as sporadic TAD (STAD). So far, the genetic basis of STAD remains unknown. Whole exome sequencing was performed in 223 STAD patients and 414 healthy controls from the Chinese Han population (N = 637). After population structure and genetic relationship and ancestry analyses, we used the optimal sequence kernel association...

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PMID: 34047934
DOI: 10.1007/s11684-020-0826-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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