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Article

TAP1 down-regulation elicits immune escape and poor prognosis in colorectal cancer

7 Aug 2017

Abstract excerpt

The anti-tumor immune response has been shown to be of great prognostic importance in colorectal cancer (CRC) and so has the tumors ability for immune evasion. Our aim of this study was to investigate tumor factors that influence immunity. We used a gene expression array to search for potential mechanisms of tumor immune escape.One candidate gene identified was TAP1, involved in antigen presentation by MHC class...

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PMID: 29147604
DOI: 10.1080/2162402x.2017.1356143

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