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Article

TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2

27 May 2021

Abstract excerpt

Antiviral therapeutics are a front-line defense against virally induced diseases. Because viruses frequently mutate to escape direct inhibition of viral proteins, there is interest in targeting the host proteins that the virus must co-opt to complete its replication cycle. However, a detailed understanding of the interactions between the virus and the host cell is necessary in order to facilitate development of...

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PMID: 34043740
DOI: 10.1371/journal.ppat.1009599

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