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Human Coronavirus: Host-Pathogen Interaction

21 Jun 2019

Abstract excerpt

Human coronavirus (HCoV) infection causes respiratory diseases with mild to severe outcomes. In the last 15 years, we have witnessed the emergence of two zoonotic, highly pathogenic HCoVs: severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Replication of HCoV is regulated by a diversity of host factors and induces drastic alterations in cellular...

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PMID: 31226023
DOI: 10.1146/annurev-micro-020518-115759

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