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Kinship of conditionally immortalized cells derived from fetal bone to human bone-derived mesenchymal stroma cells

25 May 2021

Abstract excerpt

The human fetal osteoblast cell line (hFOB 1.19) has been proposed as an accessible experimental model for study of osteoblast biology relating to drug development and biomaterial engineering. For their multilineage differentiation potential, hFOB has been compared to human mesenchymal progenitor cells and used to investigate bone-metabolism in vitro. Hereby, we studied whether and to what extent the...

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PMID: 34035368
DOI: 10.1038/s41598-021-90161-2

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