Cultured Cell Line Models of Neuronal Differentiation: NT2, PC12, and SK-N-MC.

doi:10.1007/978-1-0716-1437-2_3

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Article

Cultured Cell Line Models of Neuronal Differentiation: NT2, PC12, and SK-N-MC.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Darbinian Nune

Abstract excerpt

The lack of a convenient, easily maintained, and inexpensive in vitro human neuronal model to study neurodegenerative diseases prompted us to develop a rapid, 1-h differentiated neuronal cell model based on human NT2 cells and C3 transferase. Here, we describe the rapid differentiation of human neuronal NT2 cells, and the differentiation, transduction, and transfection of human SK-N-MC cells and rat PC12 cells to...

Topics

ADP Ribose Transferases
Adrenal Gland Neoplasms
Animals
Botulinum Toxins
Cell Culture Techniques
Humans
Neuroblastoma
Neurogenesis
Neuronal Outgrowth
Neurons
PC12 Cells
Phenotype
Pheochromocytoma
Rats
Teratocarcinoma
Transfection
Tretinoin

Source

Open in PubMed

Identifiers

PMID: 34033075
DOI: 10.1007/978-1-0716-1437-2_3

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