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Article

RTEL1 influences the abundance and localization of TERRA RNA

21 May 2021

Abstract excerpt

Telomere repeat containing RNAs (TERRAs) are a family of long non-coding RNAs transcribed from the subtelomeric regions of eukaryotic chromosomes. TERRA transcripts can form R-loops at chromosome ends; however the importance of these structures or the regulation of TERRA expression and retention in telomeric R-loops remain unclear. Here, we show that the RTEL1 (Regulator of Telomere Length 1) helicase influences...

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PMID: 34021146
DOI: 10.1038/s41467-021-23299-2

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