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Article

The protective role of YTHDF1-knock down macrophages on the immune paralysis of severe sepsis rats with ECMO.

Microvascular research - 1 Sept 2021

Xing Yan, Cheng Dongliang, Shi Changsong, Shen Zhiqiang

Abstract excerpt

OBJECTIVE: To examine the role of YTHDF1 knock-down macrophages on the immunity of severe sepsis rats with ECMO. METHODS: 15 SD rats were randomly allocated into 3 groups: mild sepsis (I), severe sepsis with ECMO (II), and YTHDF1 knock-down macrophages treatment groups (III). Blood biochemical indexes, different immune factors and brain changes were detected by RT-PCR, ELISA, ELISPOT and HE staining. Isolated...

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Identifiers

PMID: 34015275
DOI: 10.1016/j.mvr.2021.104178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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