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Article

Cell-scale biophysical determinants of cell competition in epithelia.

eLife - 20 May 2021

Gradeci Daniel, Bove Anna, Vallardi Giulia, Lowe Alan R, Banerjee Shiladitya, Charras Guillaume

Abstract excerpt

How cells with different genetic makeups compete in tissues is an outstanding question in developmental biology and cancer research. Studies in recent years have revealed that cell competition can either be driven by short-range biochemical signalling or by long-range mechanical stresses in the tissue. To date, cell competition has generally been characterised at the population scale, leaving the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34014166
DOI: 10.7554/eLife.61011
PMCID: PMC8137148

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