Article
Cellular Potts Modeling of Tumor Growth, Tumor Invasion, and Tumor Evolution
1 Jan 2013
Abstract excerpt
Despite a growing wealth of available molecular data, the growth of tumors, invasion of tumors into healthy tissue, and response of tumors to therapies are still poorly understood. Although genetic mutations are in general the first step in the development of a cancer, for the mutated cell to persist in a tissue, it must compete against the other, healthy or diseased cells, for example by becoming more motile,...
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