Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational landscape of multiple primary lung cancers and its correlation with non-intrinsic risk factors.

Scientific reports - 11 Mar 2021

Izumi Motohiro, Oyanagi Jun, Sawa Kenji, Fukui Mitsuru, Ogawa Koichi, Matsumoto Yoshiya, Tani Yoko, Suzumura Tomohiro, Watanabe Tetsuya, Kaneda Hiroyasu, Mitsuoka Shigeki, Asai Kazuhisa, Ohsawa Masahiko, Yamamoto Nobuyuki, Koh Yasuhiro, Kawaguchi Tomoya

Abstract excerpt

Multiple primary lung cancers (MPLCs) harbour various genetic profiles among the tumours, even from individuals with same non-intrinsic risk factors. Paired mutational analyses were performed to obtain a census of mutational events in MPLC and assess their relationship with non-intrinsic risk factors. Thirty-eight surgical specimens from 17 patients diagnosed as MPLC were used. Extracted DNAs were sequenced for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer Genomics and Diagnostics

Share to Lung Cancer Treatments and Mutations

Share to Lung Neoplasms

Share to Mutation

Share to Risk Factors

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 33707471
DOI: 10.1038/s41598-021-83609-y
PMCID: PMC7952588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational landscape of multiple primary lung cancers and its correlation with non-intrinsic risk factors.PMID 33707471Read ↗

Different driver gene mutations in patients with synchronous multiple primary lung cancers: a case report.Semantic proximity Read ↗

Distinct gene mutation profiles among multiple and single primary lung adenocarcinomaSemantic proximity Read ↗

Mutational analysis of multiple lung cancers: Discrimination between primary and metastatic lung cancers by genomic profile.Semantic proximity Read ↗

Clinical and genetic characteristics of early-stage multiple primary and independent primary lung adenocarcinoma patients.Semantic proximity Read ↗

Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers.Semantic proximity Read ↗

Genomic characteristics and immune landscape of super multiple primary lung cancer.Semantic proximity Read ↗

Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancerSemantic proximity Read ↗

Genomic and Clinical Significance of Multiple Primary Lung Cancers as Determined by Next-Generation Sequencing.Semantic proximity Read ↗

Presentation of EGFR mutations in 162 family probands with multiple primary lung cancerSemantic proximity Read ↗

Using molecular characteristics to distinguish multiple primary lung cancers and intrapulmonary metastases.Semantic proximity Read ↗

Phenotype-genotype correlation in multiple primary lung cancer patients in China.Semantic proximity Read ↗

Genomic heterogeneity of multiple synchronous lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.