Article
MiR-3168, miR-6125, and miR-4718 as potential predictors of cisplatin-induced nephrotoxicity in patients with head and neck cancer.
BMC cancer - 19 May 2021
Quintanilha Julia C F, Cursino Maria A, Borges Jessica B, Torso Nadine G, Bastos Larissa B, Oliveira Juliana M, Cobaxo Thiago S, Pincinato Eder C, Hirata Mario H, Geraldo Murilo V, Lima Carmen S P, Moriel Patricia
Abstract excerpt
BACKGROUND: No biomarker is available for identifying cancer patients at risk of developing nephrotoxicity when treated with cisplatin. METHODS: We performed microRNA (miRNA) sequencing using plasma collected 5 days after cisplatin treatment (D5) from twelve patients with head and neck cancer with and without nephrotoxicity (grade ≥ 2 increased serum creatinine). The most differentially expressed miRNAs between...
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