Article
MicroRNAs as prognostic molecular signatures in renal cell carcinoma: a systematic review and meta-analysis.
Oncotarget - 20 Oct 2015
Gu Liangyou, Li Hongzhao, Chen Luyao, Ma Xin, Gao Yu, Li Xintao, Zhang Yu, Fan Yang, Zhang Xu
Abstract excerpt
This is a systematic review of studies investigating the prognostic value of different microRNAs (miRs) in renal cell carcinoma (RCC). Twenty-seven relevant studies were identified, with a total of 2578 subjects. We found that elevated expression of miR-21, miR-1260b, miR-210, miR-100, miR-125b, miR-221, miR-630, and miR-497 was associated with a poor prognosis in RCC patients. Conversely, decreased expression of...
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