Article
Meta-analysis of variation suggests that embracing variability improves both replicability and generalizability in preclinical research.
PLoS biology - 1 May 2021
Usui Takuji, Macleod Malcolm R, McCann Sarah K, Senior Alistair M, Nakagawa Shinichi
Abstract excerpt
The replicability of research results has been a cause of increasing concern to the scientific community. The long-held belief that experimental standardization begets replicability has also been recently challenged, with the observation that the reduction of variability within studies can lead to idiosyncratic, lab-specific results that cannot be replicated. An alternative approach is to, instead, deliberately...
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