Article
Clinicopathologic and Genomic Characterization of Inflammatory Myofibroblastic Tumors of the Head and Neck: Highlighting a Novel Fusion and Potential Diagnostic Pitfall.
The American journal of surgical pathology - 1 Dec 2021
Kerr Darcy A, Thompson Lester D R, Tafe Laura J, Jo Vickie Y, Neyaz Azfar, Divakar Prashanthi, Paydarfar Joseph A, Pastel David A, Shirai Keisuke, John Ivy, Seethala Raja R, Salgado Claudia M, Deshpande Vikram, Bridge Julia A, Kashofer Karl, Brčić Iva, Linos Konstantinos
Abstract excerpt
Inflammatory myofibroblastic tumor (IMT) is a distinctive fibroblastic and myofibroblastic spindle cell neoplasm with an accompanying inflammatory cell infiltrate and frequent receptor tyrosine kinase activation at the molecular level. The tumor may recur and rarely metastasizes. IMT is rare in the head and neck region, and limited information is available about its clinicopathologic and molecular characteristics...
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