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Article

Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions

29 May 2014

Abstract excerpt

UNLABELLED: Inflammatory myofibroblastic tumor (IMT) is a neoplasm that typically occurs in children. The genetic landscape of this tumor is incompletely understood and therapeutic options are limited. Although 50% of IMTs harbor anaplastic lymphoma kinase (ALK) rearrangements, no therapeutic targets have been identified in ALK-negative tumors. We report for the first time that IMTs harbor other actionable...

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PMID: 24875859
DOI: 10.1158/2159-8290.cd-14-0377

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