Article
Inflammatory myofibroblastic tumor with predominant anaplastic lymphoma kinase-positive cells lacking a myofibroblastic phenotype.
Pathology international - 1 Jun 2003
Hisaoka Masanori, Shimajiri Shohei, Matsuki Yasumasa, Meis-Kindblom Jeanne M, Kindblom Lars-Gunnar, Li Xiao-Qiu, Wang Jian, Hashimoto Hiroshi
Abstract excerpt
Inflammatory myofibroblastic tumor (IMT), synonymously referred to as inflammatory pseudotumor, is a distinctive mesenchymal lesion composed of spindle cells displaying morphological features of myofibroblasts admixed with considerable numbers of inflammatory cells. Recent genetic and molecular studies have shown that a subset of IMT is characterized by the expression of altered anaplastic lymphoma kinase (ALK)...
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