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A novel TPD52L2-ROS1 gene fusion expanding the molecular alterations in inflammatory myofibroblastic tumor: case report and literature review

2022-11-23

Abstract excerpt

<h4>Background: </h4> Inflammatory myofibroblastic tumor (IMT) is a distinctive tumor composed of spindle cells accompanied by mixed inflammatory cells, and immunohistochemical positivity for ALK (anaplastic lymphoma kinase protein) can be detected in half of IMTs. The diagnosis of ALK-negative IMT could be a challenge. Recently, the fusions of some kinase genes, such as RET , NTRK1 , ROS1 , etc., are revealed in...

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Literature Corpus work
0fb10731-11a4-5107-ac31-d5a826b666ce
DOI
10.21203/rs.3.rs-2290230/v1
Open publication

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