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Article

Deciphering biological characteristics of tumorigenic subpopulations in human colorectal cancer reveals cellular plasticity

1 Jan 2016

Abstract excerpt

Background: It is supposed that human colorectal cancer consists of a phenotypically distinct population of tumorigenic cancer cells known as cancer stem cells (CSCs) which play a pivotal role in cancer progression, maintenance, metastasis, and the relapse. The aim of this effort was to investigate and compare biological characterizations of CD133 + with CD133 − cell subsets isolated from both primary and...

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PMID: 27904609
DOI: 10.4103/1735-1995.187355

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