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Article

BAG Family Members as Mitophagy Regulators in Mammals

15 Feb 2022

Abstract excerpt

The BCL-2-associated athanogene (BAG) family is a multifunctional group of co-chaperones that are evolutionarily conserved from yeast to mammals. In addition to their common BAG domain, these proteins contain, in their sequences, many specific domains/motifs required for their various functions in cellular quality control, such as autophagy, apoptosis, and proteasomal degradation of misfolded proteins. The BAG...

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PMID: 35203329
DOI: 10.3390/cells11040681

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