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Article

Role of miR-506 in ulcerative colitis associated with primary sclerosing cholangitis.

Scientific reports - 12 May 2021

Kempinska-Podhorodecka Agnieszka, Adamowicz Monika, Ostrycharz Ewa, Chmielarz Mateusz, Wójcicki Maciej, Milkiewicz Piotr, Milkiewicz Malgorzata

Abstract excerpt

Primary sclerosing cholangitis (PSC) is commonly accompanied by ulcerative colitis (UC). MicroRNA-506 modulates expression of genes which are essential for sphingosine-mediated signaling pathway and intestinal mucosa protection. We investigated whether miR-506 and its target genes are involved in phenotypic presentations of colonic inflammation and/or neoplasia. We analyzed serum and colon tissue samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33980925
DOI: 10.1038/s41598-021-89631-4
PMCID: PMC8114918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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