Primary Progressive Aphasia Associated With GRN Mutations: New Insights Into the Nonamyloid Logopenic Variant.

doi:10.1212/WNL.0000000000012174

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Primary Progressive Aphasia Associated With GRN Mutations: New Insights Into the Nonamyloid Logopenic Variant.

Neurology - 6 Jul 2021

Saracino Dario, Ferrieux Sophie, Noguès-Lassiaille Marie, Houot Marion, Funkiewiez Aurélie, Sellami Leila, Deramecourt Vincent, Pasquier Florence, Couratier Philippe, Pariente Jérémie, Géraudie Amandine, Epelbaum Stéphane, Wallon David, Hannequin Didier, Martinaud Olivier, Clot Fabienne, Camuzat Agnès, Bottani Simona, Rinaldi Daisy, Auriacombe Sophie, Sarazin Marie, Didic Mira, Boutoleau-Bretonnière Claire, Thauvin-Robinet Christel, Lagarde Julien, Roué-Jagot Carole, Sellal François, Gabelle Audrey, Etcharry-Bouyx Frédérique, Morin Alexandre, Coppola Cinzia, Levy Richard, Dubois Bruno, Brice Alexis, Colliot Olivier, Gorno-Tempini Maria Luisa, Teichmann Marc, Migliaccio Raffaella, Le Ber Isabelle

Abstract excerpt

OBJECTIVE: To determine relative frequencies and linguistic profiles of primary progressive aphasia (PPA) variants associated with GRN (progranulin) mutations and to study their neuroanatomic correlates. METHODS: Patients with PPA carrying GRN mutations (PPA-GRN) were selected among a national prospective research cohort of 1,696 patients with frontotemporal dementia, including 235 patients with PPA. All patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aphasia, Primary Progressive

Share to Atrophy

Share to Frontotemporal Dementia

Share to Language Tests

Share to Neuropsychological Tests

Share to Progranulins

Share to Speech

Share to Tomography, Emission-Computed, Single-Photon

Source

Open in PubMed

Identifiers

PMID: 33980708
DOI: 10.1212/WNL.0000000000012174

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary Progressive Aphasia Associated With GRN Mutations: New Insights Into the Nonamyloid Logopenic Variant.PMID 33980708Read ↗

Progranulin-associated PiB-negative logopenic primary progressive aphasia.Semantic proximity Read ↗

Classification of primary progressive aphasia: challenges and complexitiesSemantic proximity Read ↗

A novel granulin mutation in logopenic variant primary progressive aphasias: Case report and literature reviewSemantic proximity Read ↗

Neuroimaging and biochemical markers in the three variants of primary progressive aphasia.Semantic proximity Read ↗

Amyloid PET Positivity in Different Primary Progressive Aphasia Phenotypes.Semantic proximity Read ↗

Primary progressive aphasia: six questions in search of an answer.Semantic proximity Read ↗

Dominant frontotemporal dementia mutations in 140 cases of primary progressive aphasia and speech apraxia.Semantic proximity Read ↗

Clinical dimensions along the progressive nonfluent variant primary progressive aphasia spectrumSemantic proximity Read ↗

GRN and MAPT Mutations in 2 Frontotemporal Dementia Research Centers in Brazil.Semantic proximity Read ↗

Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia.Semantic proximity Read ↗

Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions.Semantic proximity Read ↗

Progranulin-associated primary progressive aphasia: a distinct phenotype?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.