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Azetidine-Bearing Non-Ribosomal Peptides, Bonnevillamides D and E, Isolated from a Carrion Beetle-Associated Actinomycete

12 May 2021

Abstract excerpt

Two new nonribosomal peptides, bonnevillamides D and E ( 1 and 2 ), have been discovered in Streptomyces sp. UTZ13 isolated from the carrion beetle, Nicrophorus concolor . Combinational analysis of the UV, MS, and NMR spectroscopic data revealed that their planar structures were comprised of dichlorinated linear peptides containing nonproteinogenic amino acid residues, such as 4-methylazetidinecarboxylic acid and...

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PMID: 33979513
DOI: 10.1021/acs.joc.1c00360

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