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A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation

11 May 2021

Abstract excerpt

Although human antibodies elicited by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein are profoundly boosted upon infection, little is known about the function of N-reactive antibodies. Herein, we isolate and profile a panel of 32 N protein-specific monoclonal antibodies (mAbs) from a quick recovery coronavirus disease-19 (COVID-19) convalescent patient who has dominant...

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PMID: 33976229
DOI: 10.1038/s41467-021-23036-9

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