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Article

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development

1 Jan 2017

Abstract excerpt

Branching morphogenesis creates arborized epithelial networks. In the mammalian kidney, an epithelial progenitor pool at ureteric branch tips (UBT) creates the urine-transporting collecting system. Using region-specific mouse reporter strains, we performed an RNA-seq screen, identifying tip and stalk enriched gene sets in the developing collecting duct system. Detailed in situ hybridization studies of...

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PMID: 28705898
DOI: 10.1242/dev.149112

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