Article
How do Mutations of Mycobacterium Genes Cause Drug Resistance in Tuberculosis?
Current pharmaceutical biotechnology - 1 Jan 2024
Hou Kaiying, Jabeen Riffat, Sun Lin, Wei Jianshe
Abstract excerpt
A steady increase in the prevalence of drug-resistant tuberculosis (DR-TB) has already been reported in Pakistan. In addition, DR-TB is gradually changing from one-drug resistance to multi-drug resistance, which is a serious challenge for tuberculosis treatment. This review provides an overview of the anti-tuberculosis drugs and focuses on the molecular mechanisms of drug resistance in Mycobacterium tuberculosis,...
Topics
- Antitubercular Agents
- Mycobacterium tuberculosis
- Humans
- Mutation
- Tuberculosis, Multidrug-Resistant
- Drug Resistance, Multiple, Bacterial
- Bacterial Proteins
