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Article

Polymorphism in BACH2 gene is a marker of polyglandular autoimmunity

8 May 2021

Abstract excerpt

PURPOSE: Genetically predisposed individuals may develop several autoimmune diseases-autoimmune polyendocrine syndromes (APS). APS types 2-4, are complex disorders, which combine various organ-specific autoimmune conditions. Recent reports support the considerable role of the BACH2 gene in immune cell differentiation and shifting the T-cell balance towards regulatory T-cells. BACH2 polymorphisms are associated...

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PMID: 33966174
DOI: 10.1007/s12020-021-02743-9

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