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Tau mRNA Metabolism in Neurodegenerative Diseases: A Tangle Journey

23 Jan 2022

Abstract excerpt

Tau proteins are known to be mainly involved in regulation of microtubule dynamics. Besides this function, which is critical for axonal transport and signal transduction, tau proteins also have other roles in neurons. Moreover, tau proteins are turned into aggregates and consequently trigger many neurodegenerative diseases termed tauopathies, of which Alzheimer's disease (AD) is the figurehead. Such pathological...

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PMID: 35203451
DOI: 10.3390/biomedicines10020241

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