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Article

Redd1 knockdown prevents doxorubicin-induced cardiac senescence.

Aging - 6 May 2021

Huang Pianpian, Bai Lijuan, Liu Lihua, Fu Jun, Wu Kefei, Liu Hongxia, Liu Yun, Qi Benming, Qi Benling

Abstract excerpt

Regulated in development and DNA damage response-1 (Redd1) is a stress-response gene that is transcriptionally induced by diverse stressful stimuli to influence cellular growth and survival. Although evidence suggests that aging may drive Redd1 expression in skeletal muscles, the expression patterns and functions of Redd1 in senescent cardiomyocytes remain unspecified. To address this issue, in vitro and in vivo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33962393
DOI: 10.18632/aging.202972
PMCID: PMC8202877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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